HOLE is a program that allows the analysis and visualisation of the pore dimensions of the holes through molecular structures of ion channels. To use it you must supply a file in pdb format containing the Cartesian coordinates of atoms that comprise the molecular structure of the channel you are interested in. This could be the result of experimental structure determination (X-ray crystallography or NMR techniques) or modelling methods.
If you want to link to this page (or subdirectories) - please use url http://hole.biop.ox.ac.uk/hole
