The HOLE suite homepage: hole.biop.ox.ac.uk/hole

The HOLE suite homepage: hole.biop.ox.ac.uk/hole

This is the new HOLE homepage hosted by the Sansom Laboratory at the University of Oxford

HOLE is a program that allows the analysis and visualisation of the pore dimensions of the holes through molecular structures of ion channels. To use it you must supply a file in pdb format containing the Cartesian coordinates of atoms that comprise the molecular structure of the channel you are interested in. This could be the result of experimental structure determination (X-ray crystallography or NMR techniques) or modelling methods.

  • Download hole to run on your own computer.
  • Prototype hole web interface (beta test prototype - not yet for general use)
  • Help including program documentation, contact information...
  • Oliver Smart homepage for other information of interest (old lecture notes).

    If you want to link to this page (or subdirectories) - please use url http://hole.biop.ox.ac.uk/hole

    HOLE in structure HOLE graph
    Visualisation of the pore dimensions of a NMR structure of gramicidin A (1grm). The top picture shows the hole surface within the structure visualized with the vmd program. Results can also be displayed as a graph (lower). Further details

    Click here to try a javamage 3D visualization of the hole surface within the molecule in your web browser (new).


    Copyright 2004 Oliver S. Smart